A point mutation is a kind of mutation in RNA or DNA, that is, the genetic substance of the cell, in which one single nucleotide base is deleted, added, or changed. It is a wide term applied for the kind of mutation in which only one nucleotide in the arrangement of the gene is substituted by the other nucleotide.
The point mutations most usually include the substitution of one base with another that alters the complementary base as well in DNA. The term point mutation also involves deletions or insertions of a single pair of the base.