During the times of fasting, type of 'fuel molecule' that liver cells use to generate energy for its own use is : fatty acids.
Fasting involves a radical change in cellular physiology and metabolism and blood glucose provides the body with sufficient energy through glycolysis. During fast, blood glucose levels maintenance relies on glycogen stores in the liver and skeletal muscle
During short-term fasting periods, liver produces and releases glucose through glycogenolysis. During prolonged fasting, glycogen is reduced and hepatocytes synthesizes glucose through gluconeogenesis using lactate, pyruvate, glycerol, and amino acids
Fatty acid oxidation is the mitochondrial aerobic process of breaking down fatty acid into acetyl-CoA units and fatty acids move in this pathway as CoA derivatives utilizing NAD and FAD.
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