The most likely organelle that is affected by hepatitis C in liver cells should be ribosomes due they synthesize proteins including albumin.
The ribosomes are well known to be the protein factories of cells that use amino acids as building blocks to synthesize proteins.
Ribosomes are be affected by hepatitis C because this RNA virus binds to the ribosome to induce a switch in the process of protein translation initiation to the second step (protein elongation).
Albumin is one of the most common proteins in the bloodstream which is heavily synthesized by the ribosomes present in all cell types.
In conclusion, the most likely organelle that is affected by hepatitis C in liver cells should be ribosomes due they synthesize proteins including albumin.
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