Respuesta :
Chronic stimulation results in an exhausted phenotype in CD8+ T lymphocytes that is defined by the production of inhibitory receptors, down-modulation of effector function, and metabolic abnormalities. T cell fatigue restricts the removal of virus-infected or tumour cells but protects against severe immunopathology.
What is Transcription factor ?
A transcription factor is a molecule that regulates a gene's function by deciding whether its DNA (deoxyribonucleic acid) is converted into RNA (ribonucleic acid). Using the DNA of the gene as a template, the enzyme RNA polymerase catalyses the chemical processes that result in the synthesis of RNA.
- The SRY protein is another illustration of a transcription factor that participates in development. For sex differentiation to occur during human development, the SRY protein is required. The SRY protein activates genes involved in the development of the male reproductive system.
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