Beta thalassemia is caused by point mutations and sometimes deletions in the beta-globin gene of the 11th chromosome.
This is a type of blood disorder which is inherited from the parents resulting in reduced synthesis of haemoglobin in the body reducing the oxygen-carrying capacity of the blood.
Beta thalassemia is of two types. First is Beta thalassemia major; it is a severe form of this disorder and people suffering from this condition require blood transfusions very frequently. The second is Beta thalassemia minor which has only a few or no symptoms.
Beta thalassemia cannot be treated by iron supplements as lack of iron is not the cause of this disorder. It is a genetic disorder which is managed by folic acid supplements and regular blood transfusions.
Therefore, chromosome 11 demonstrates a partial or full gene loci deletion in various forms of Beta-thalassemia.
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