The DNA kink of 80˚ is induced by tight binding of TBP which ultimately displaces the binding of TAFs 11 and 13.
The protein which bind to TATA-binding protein during the initiation transcription is called as TAFs are the component of TFIID multimeric protein complex which is a transcription initiation factor .
The key component of transcription initiation machinery, and play a role in core promoter recognition, assembly of the pre-initiation complex
These have a signature domain named N-terminal histone-like fold domain (HFD).
Hence, DNA kink of 80˚ is induced by tight binding of TBP
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