The result of a cross between two agouti mice of genotype nnaa are albino offspring because mice with genotype nn are albino (pigment production is blocked by epistasis).
Epistasis is a genetic phenomenon where the presence of a gene variant alters a phenotype influenced by other genes.
A gene is epistatic when a variant (allele) can alter the expression of another gene in the same signaling pathway.
Epistatic interactions are very common in nature and many traits are influenced by this type of interaction.
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