Most cells do not get very large in overall size. Which factor(s) contribute to this?

a.
In order for a cell to survive, it needs to be able to supply itself with adequate raw materials and eliminate all metabolic wastes across the plasma membrane.

b.
In order for a cell to survive, it needs to be able to supply itself with adequate metabolic waste products and eliminate all raw materials across the plasma membrane.

c.
The volume of a cell decreases as the surface area increases.

d.
One large cell is efficient and effective at supplying itself with adequate raw materials.

e.
As the cell increases in size, it requires more raw materials which have no problem crossing the plasma membrane since the surface area increases at the same rate as the volume of the cell.