The impact of government instability on the distribution of resources to combat diseases, distribute medications in Africa.The instability in Africa has been long since dated back to the colonial period.The crisis in Africa because of rebellion, corruption, kidnapping, recession, inflation has impacted the nation growth.Government stability is only possible through overcoming the crisis that existed in Africa.The issue of poverty and diseases has long existed in Africa, and to overcome it, the government has to implement policies and schemes.Therefore we can conclude that government uncertainty is a reason for the lack of resources to fight diseases, distribute medications across Africa.