Answer: In order for a substitution reaction to take place, at a minimum, loss of a leaving group and nucleophilic attack are needed.
Explanation:
When one group in a molecule is replaced by another one then it is called a substitution reaction.
For a substitution reaction reaction to occur at a minimum, it is necessary to have a leaving group that helps in creating a carbocation and hence a nucleophile can easily attack.
For example, [tex]CH_{4} + Cl_{2} + h\nu \rightarrow CH_{3}Cl + HCl[/tex]
Thus, we can conclude that in order for a substitution reaction to take place, at a minimum, loss of a leaving group and nucleophilic attack are needed.