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Answer:
Covering approximately 800 miles, the Santa Fe Trail extends from Independence, Missouri to present day Santa Fe, New Mexico. The Trail originally began in Franklin, Missouri, but the trail head was moved to Fort Osage and, by 1827, to Independence. ... The Santa Fe Trail was first used in 1821 by William Becknell.
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It starts at Independence, Missouri and ends at present day Santa Fe, New Mexico.
P.S. the trail is 869.9 miles.
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