contestada

What enzyme catalyses the reaction of PRPP transfer to hypoxanthine with
formation of IMP?

Respuesta :

Jicai

Answer:

HPRT

Explanation:

HPRT catalyzes the salvage reactions of hypoxanthine and guanine with PRPP to form IMP and GMP

The formation of GMP from IMP requires oxidation at C-2 of the purine ring, followed by a glutamine-dependent amidotransferase reaction that replaces the oxygen on C-2 with an amino group to yield 2-amino,6-oxy purine nucleoside monophosphate, or as this compound is commonly known, guanosine monophosphate.