Answer:
D. Adding the Bill of Rights to the Constitution
Explanation:
The major problem that led to the Great Debate was that the Federalist, led by Alexander Hamilton wanted to ratify the Constitution but the Anti-Federalist did not want to.
The Anti Federalist wanted to include the Bill of Rights to checkmate the central government because it had too much power.
Therefore, both parties agreed to ratify the Constitution once the Federalist consented to add the Bill of Rights.