Answer:
The consumption of a drug that inhibits or block the enzyme primase will have problems for the replication of DNA, since it is not possible to synthesize a new strand without this enzyme.
Explanation:
During DNA replication, the enzyme primase is responsible for synthesizing the primers, RNA fragments necessary for the DNA polymerase III to synthesize the new DNA strand.
If for any reason the action of the primase is blocked, the primer could not be synthesized and the effect of DNA polymerase III would be null, so the new DNA strand could not be synthesized.
In DNA replication, the primase contributes to the formation of small fragments of DNA, by the action of polymerase III, which are called Okazaki fragments. These fragments will require the action of another enzyme, ligase, in order to form a continuous DNA strand.