What are the pros and cons of CRISPR-cas9

For example, the CRISPR-Cas9 system has more target sites than ZFNs and TALENs, and Cas9 has many variants that can be used in a variety of studies. Moreover, the system is extremely easy to use and can be executed in almost any laboratory.

The most important advantages of CRISPR/Cas9 over other genome editing technologies is its simplicity and efficiency. Since it can be applied directly in embryo, CRISPR/Cas9 reduces the time required to modify target genes compared to gene targeting technologies based on the use of embryonic stem (ES) cells.

Disadvantages of CRISPR technology: CRISPR-Cas9 off-target; The effect of off-target can alter the function of a gene and may result in genomic instability, hindering it prospective and application in clinical procedure.

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afrancois1717 afrancois1717 · Answer 2 · 2020-09-18T03:59:27+02:00

afrancois1717 afrancois1717

18-09-2020

Answer:

One of the major pros of crispr-cas9 is that it could potentially wipe-out many genetic diseases and could even be used to develop a successful cancer therapy.

The main con would be the ethics. In the future an individual could select their own desired traits for their offspring. The wealthy would have a larger advantage which could increase the social gap.

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