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nilnelso50

The fragility of cancer cells when they undergo division serves as a critical intervention point in chemotherapy. ... Despite being the shortest phase of the cell-cycle, mitosis ... Therefore, there is a strong interest in developing novel drugs that do not affect .... cells. Plk1 is the most thoroughly studied member.

CassiusKiel

If you intend to study Taxol, you'd be most interested in cells during metaphase/anaphase. This is because Taxol deleteriously affects the ability of cancer cells to properly assemble a mitotic spindle, pass the metaphase/anaphase checkpoint, and produce progeny.

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